LONG SPAN DNA PAIRED-END-TAG (DNA-PET) SEQUENCING STRATEGY FOR THE INTERROGATION OF GENOMIC STRUCTURAL MUTATIONS AND FUSION-POINT-GUIDED RECONSTRUCTION OF AMPLICONS.

Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons.

Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements RWgift are a hallmark of cancer.While genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify genomic SVs, the current application of PET sequencing with short insert size DNA can be insuffic

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The Role of Adipokines in Pancreatic Cancer

In modern society, inappropriate diets and other lifestyle habits have made obesity an increasingly prominent health problem.Pancreatic cancer (PC), a kind of highly aggressive malignant tumor, is known as a silent assassin and is the seventh leading cause of cancer death worldwide, pushing modern medicine beyond help.Adipokines are coming into not

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Safety and authenticity risks in heritage food preparation at different types of food service establishments: A case study of Saudi Arabia

In Saudi Arabia, tourism is becoming increasingly popular, and forms an essential element of Vision 2030.Accordingly, food service establishments (FSEs) including hotels, ordinary restaurants, heritage restaurants and productive families (i.e., home-based catering) provide heritage cuisine to tourists.This study aimed to assess the authenticity and

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Immune Response to Third and Fourth COVID-19 Vaccination in Hemodialysis Patients and Kidney Transplant Recipients

Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a serious hazard for hemodialysis (HD) patients and kidney transplant (KTX) recipients as they suffer from an impaired immune response to SARS-CoV-2 vaccination.In addition, a definition of SARS-CoV-2 IgG titer that indicates a sufficient immune response, especially against new om

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